| 设为主页 | 保存桌面 | 手机版 | 二维码
普通会员

北京义翘神州生物技术有限公司

基因,重组蛋白,抗体

新闻中心
  • 暂无新闻
产品分类
联系方式
  • 联系人:郭星
  • 电话:86-010-51029968
  • 邮件:Order@SinoBiological.com
  • 传真:86-010-51029969
您当前的位置:首页 » 供应产品 » 纤维胶原蛋白1
纤维胶原蛋白1
点击图片查看原图
产品: 浏览次数:2144纤维胶原蛋白1 
型号: 纤维胶原蛋白1
规格: 100µg
单价: 面议
最小起订量:
供货总量:
发货期限: 自买家付款之日起 3 天内发货
有效期至: 长期有效
最后更新: 2010-06-09 16:37
  询价
详细信息

Mast cell protease 1 Protein Datasheet

 

MCPT1 Protein Price Information

  • 50ug:  Inquiring Price;
  • 200ug:  Inquiring Price;
  • ≥1mg Bulk:  Inquiring Price

MCPT1 Protein Product Information

MCPT1 Synonym : Mcpt1,AV080368, Mcp-1
Protein Construction: A DNA sequence encoding the mouse MCPT1 (NP_032596.1) (Met 1- Lys 246) was expressed with a polyhistidine tag at the C-terminus.
Source: Mouse
Expression Host: Human Cells

MCPT1 Protein QC Testing

Purity: > 97%, as determined by SDS-PAGE SDS-PAGE:
SDS-PAGE
Endotoxin: < 1.0 EU per 1μg of the protein as determined by the LAL method.
Stability: Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N terminal: Glu 19
Molecular Mass: The secreted recombinant mouse MCPT1 consists of 239 amino acids and has a predicted molecular mass of 26.8 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rm MCPT1 is approximately 32-34 kDa due to glycosylation.
Formulation: Supplied as a 0.2m filtered solution of PBS, pH7.4

MCPT1 Protein Usage Guide

Storage: Store it under sterile conditions at -70℃ immediately after receipt. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: Follow the instructions on the vial. Centrifuge the vial at 4℃ before opening to recover the entire contents.

MCPT1 Protein Description

Mouse Mast Cell Protease 1 (MMCP-1) , also known as MCP-1, MCPT-1 and β-chymase, is a member of the Chymase family of chymotrypsin-like serine proteases. It is a 26 kDa β-chymase that is a component of mast cell granules. MCPT-1 is a 226 amino acid (aa) protein that has a conserved pattern of six cysteines and one potential glycosylation site. Mature mouse and rat MCPT-1 share 76% aa identity. MCPT-1 is predominantly expressed in intestinal mucosal mast cells where it promotes mucosal permeability in intestinal allergic hypersensitivity reactions. Its activation is completed by the removal of a two residue N-terminal propeptide by a dipeptidyl peptidase (Cathepsin C). MCPT-1 is upregulated in the intestine in response to nematode infection, or in systemic mucosa in response to anaphylaxis. Like human α-chymase, MCPT-1 is capable of the conversion of angiotensin I to angiotensin II, which plays a key role in the regulation of arterial pressure.

MCPT1 Protein Related Products &Topics

  • MCPT1 Protein Related Areas:
    • Immunology>>Innate Immunity>>Mast Cell>>Mcp-1/MCPT1
  • Proteins:
  • Antibodies:

References

  1. Trong, H. L. et al., 1989,Biochemistry. 28 (1):391-395.
  2. Newlands, G. F. et al., 1993,Biochem J. 294 ( Pt 1) :127-135.
  3. Murakami, M. et al., 1995, J. Biol. Chem. 270: 2218-2223.
  4. Wastling, J. M. et al., 1998, Am. J. Pathol. 153: 491-504.
  5. Saito, K. et al., 2003, Biochem. Biophys. Res. Commun. 302: 773-777.
  6. Tsunemi, K. et al., 2004, J. Pharmacol. Exp. Ther. 309: 879-883.
询价单
0条  相关评论