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基因,重组蛋白,抗体

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重组鼠Podoplanin(平足蛋白),N-hFc
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产品: 浏览次数:797重组鼠Podoplanin(平足蛋白),N-hFc  
型号: 50256-M03H
规格: 100µg
单价: 面议
最小起订量:
供货总量:
发货期限: 自买家付款之日起 3 天内发货
有效期至: 长期有效
最后更新: 2010-06-09 16:49
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详细信息

S100 calcium binding protein A6 (calcyclin) Protein Datasheet

 

S100A6 / Calcyclin Protein Price Information

  • 200ug:  Inquiring Price;
  • ≥1mg Bulk:  Inquiring Price

S100A6 / Calcyclin Protein Product Information

S100A6 Synonym : 2A9, 5B10, CALCYCLIN, Cacy, PRA, S100a6
Protein Construction: A DNA sequence encoding the mouse S100A6 (NP_035443.1) (Met 1-Lys 89 ) was expressed.
Source: Mouse
Expression Host: E.coli

S100A6 / Calcyclin Protein QC Testing

Purity: > 98 % as determined by SDS-PAGE SDS-PAGE:
SDS-PAGE
Endotoxin: < 1.0 EU per 1μg of the protein as determined by the LAL method.
Stability: Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N terminal: Met
Molecular Mass: The recombinant mouse S100A6 consisting of 89 amino acids and has a calculated molecular mass of 10 kDa as estimated in SDS-PAGE under reducing conditions.
Formulation: Supplied as a 0.2μm filtered solution of PBS, pH7.4

S100A6 / Calcyclin Protein Usage Guide

Storage: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted and be used as soon as possible. Avoid repeated freeze-thaw cycles.
Reconstitution: Follow the instructions on the vial. Centrifuge the vial at 4℃ before opening to recover the entire contents.

S100A6 / Calcyclin Protein Description

S100 protein is a family of low molecular weight protein found in vertebrates characterized by two EF-hand calcium-binding motifs. There are at least 21 different S100 proteins, and the name is derived from the fact that the protein is 100% soluble in ammonium sulfate at neutral pH. Most S100 proteins are disulfide-linked homodimer, and is normally present in cells derived from the neural crest, chondrocytes, macrophages, dendritic cells, etc. S100 proteins have been implicated in a variety of intracellular and extracellular functions. They are involved in regulation of protein phosphorylation, transcription factors, the dynamics of cytoskeleton constituents, enzyme activities, cell growth and differentiation, and the inflammatory response. S100A6 (S100 calcium binding protein A6) is a member of the S100 family of proteins, and functions in stimulation of Ca2+-dependent insulin release, prolactin secretion, and exocytosis. Chromosomal rearrangements and altered expression of S100A6 have been implicated in melanoma. Mouse S100A6 is 99% and 96% aa identical to rat and human S100A6, respectively, and exits as monomer or disulfide-linked dimers.

S100A6 / Calcyclin Protein Related Products &Topics

  • S100A6 / Calcyclin Protein Related Areas:
    • Cancer>>Cancer Biomarkers>>S100A6
  • Proteins:
  • Antibodies:

References

  1. Schäfer, B.W. et al., 1996, Trends Biochem. Sci. 21 (4): 134–140.
  2. Donato,R. et al., 2003, Microsc. Res. Tech. 60 (6): 540–551.
  3. Nowotny, M. et al., 2003, J. Biol. Chem. 278 (29): 26923-26928.
  4. Marenholz, I. et al., 2004, Biochem. Biophys. Res. Commun. 322 (4): 1111–1122. 
  5. Nonaka D, et al., 2008, J. Cutan. Pathol. 35 (11): 1014–1019.
 
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