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基因,重组蛋白,抗体

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基质金属蛋白酶组织抑制因子 -1
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产品: 浏览次数:733基质金属蛋白酶组织抑制因子 -1 
型号: 10934-HNAH
规格: 20µg
单价: 面议
最小起订量:
供货总量:
发货期限: 自买家付款之日起 3 天内发货
有效期至: 长期有效
最后更新: 2010-06-09 16:50
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详细信息

Follistatin-like 1 Protein Datasheet

 

FSTL1 / Follistatin-like 1 Protein Price Information

  • 50ug:  Inquiring Price;
  • 200ug:  Inquiring Price;
  • ≥1mg Bulk:  Inquiring Price

FSTL1 / Follistatin-like 1 Protein Product Information

FSTL1 Synonym : FSTL1,FLJ50214, FLJ52277, FRP, FSL1
Protein Construction: A DNA sequence encoding the human FSTL1 (NP_009016.1) precursor (Met 1- Ile 308 ) with a carboxy-terminal polyhistidine tag was expressed.
Source: Human
Expression Host: Human Cells

FSTL1 / Follistatin-like 1 Protein QC Testing

Purity: > 98%, as determined by SDS-PAGE SDS-PAGE:
SDS-PAGE
Endotoxin: < 1.0 EU per 1μg of the protein as determined by the LAL method.
Stability: Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N terminal: Glu 21
Molecular Mass: The secreted recombinant human FSTL1 consists of 299 amino acids with the predicted molecular mass of 34.2 kDa. As a result of glycosylation, rhFSTL1 migrates as an approximately 47 kDa band in SDS-PAGE under reducing conditions.
Formulation: Supplied as a 0.2μm filtered solution of PBS, pH7.4

FSTL1 / Follistatin-like 1 Protein Usage Guide

Storage: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted and be used as soon as possible. Avoid repeated freeze-thaw cycles.
Reconstitution: Follow the instructions on the vial. Centrifuge the vial at 4℃ before opening to recover the entire contents.

FSTL1 / Follistatin-like 1 Protein Description

Follistatin-like 1, also known as FSTL1, is an activin-binding protein with similarity to follistatin. It contains an FS module, a follistatin-like sequence containing ten conserved cysteine residues, two EF-hand domains, a Kazal-like domain and a VWFC domain. This heparin binding protein is involved in the BMP signaling pathway, and may modulate the action of some growth factors on cell proliferation and differentiation. FSTL1 is thus suggested as a regulator of early mesoderm patterning, somitogenesis, myogenesis and neural development. FSTL1 is ubiquitously expressed in the majority of tissues in adult, with strongly expressed level in the mesenchymal component and excluded from the epithelium. In addition, this protein is thought to be an autoantigen associated with rheumatoid arthritis.

FSTL1 / Follistatin-like 1 Protein Related Products &Topics

  • FSTL1 / Follistatin-like 1 Protein Related Areas:
    • Cancer>>Growth Factor & Receptor>>TGF-beta Superfamily>>Activin/Inhibitin>>FSTL1/Follistatin Like 1
    • Immunology>>Cytokine>>TGF-beta Superfamily>>Activin/Inhibitin>>FSTL1/Follistatin Like 1
    • Immunology>>Cytokine>>TGF-beta Superfamily>> TGF-beta Superfamily Modulators>>FSTL1/Follistatin Like 1
  • Proteins:
  • Antibodies:

References

  1. Tanaka, M. et al., 1998, Int. Immunol. 10 (9): 1305–1314.
  2. Adams, D. et al., 2007, Gene Expr Patterns. 7 (4): 491-500.
  3. Ouchi, N. et al., 2008, J Biol Chem. 283 (47): 32802-32811.
  4. Chan,Q.K. et al., 2009, Carcinogenesis. 30 (1):114-121.
 
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